IFNA14

mutation — cross-omics
Cross-omicsMUTATION → MUTATIONCell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, IFNA14 mutation is significantly associated with the mutation status of many other genes, with 162 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible IFNA14-associated genes across cancer lineages are LYPD5, TRIM68, and NGLY1. Each is linked with IFNA14 in more than 1 cancer types. Because this analysis shows association rather than direction, both IFNA14-to-partner and partner-to-IFNA14 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IFNA14→partner) and Y-score (partner→IFNA14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LeukemiaLYPD5 →+5.560+4.736.003.00312
BLOOD_LeukemiaTRIM68 →+4.560+4.309.007.00712
BLOOD_LeukemiaNGLY1 →+4.560+4.309.007.00712
BLOOD_LeukemiaAPOBEC3D →+4.560+4.309.007.00711
BLOOD_LeukemiaNACA2 →+5.560+4.736.003.00311
BLOOD_LeukemiaFDX2 →+5.560+4.736.003.00311
Each partner links to its Q-omics profile. Showing the 6 strongest of 162 associations by consensus.

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