IFITM3P7

Across TCGA patient cohorts, IFITM3P7 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,202 significant associations in total. STAD shows the largest number of these associations.

The most reproducible IFITM3P7-associated GO terms across cancer lineages are Regulation of viral genome replication, Response to interferon-beta, and Negative regulation of viral genome replication. Each is linked with IFITM3P7 in more than 13 cancer types. Because this analysis shows association rather than direction, both IFITM3P7-to-partner and partner-to-IFITM3P7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of viral genome replication grouped by IFITM3P7-low versus IFITM3P7-high in LAML.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IFITM3P7→partner) and Y-score (partner→IFITM3P7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LAML	Regulation of viral genome replication →	+0.049	+0.352	<.001	<.001	3	14
LAML	Response to interferon-beta →	+0.060	+0.384	<.001	<.001	3	13
LAML	Negative regulation of viral genome replication →	+0.070	+0.401	<.001	<.001	2	14
STAD	Negative regulation of viral entry into host cell →	+0.047	+0.318	<.001	<.001	3	12
LAML	Interleukin-27-mediated signaling pathway →	+0.118	+0.288	<.001	.002	2	13
STAD	Pyrimidine nucleotide biosynthetic process →	+0.033	+0.268	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,202 associations by consensus.

Regulation of viral genome replication by IFITM3P7 expression — LAML

Explore this box plot interactively →