Across TCGA pan-cancer cohorts, IFITM3P2 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of IFITM3P2’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where IFITM3P2 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types IFITM3P2 is over-expressed in tumor, although a few such as LUAD show the opposite, repressed pattern.

HNSC, ESCA, and LUAD are the cancer types where IFITM3P2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in IFITM3P2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	All	+0.754	.002	5	view →
ESCA	All	All	+1.168	.001	3	view →
LUAD	All	IV	−1.900	.029	2	view →
KIRP	Male	II,III,IV	+0.427	.004	2	view →
KIRC	All	All	+0.568	.031	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

Exploration

Same gene, other analysis: IFITM3P2 RNA expression & survival · all IFITM3P2 data types