Across TCGA patient cohorts, IFITM2 RNA expression is significantly associated with the protein abundance of many other proteins, with 23,019 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IFITM2-associated proteins across cancer lineages are CAV1, MYO1C, and RAI14. Each is linked with IFITM2 in more than 6 cancer types. Because this analysis shows association rather than direction, both IFITM2-to-partner and partner-to-IFITM2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IFITM2→partner) and Y-score (partner→IFITM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CAV1 →	+0.886	+1.080	<.001	<.001	3	7
OV	MYO1C →	+0.673	+1.329	<.001	<.001	3	7
OV	RAI14 →	+0.439	+1.232	<.001	<.001	3	6
LSCC	PHB →	-0.323	-0.730	<.001	<.001	3	6
OV	TLN1_S1201 →	+1.539	+0.912	.004	.007	3	6
GBM	PNN →	-0.356	-0.932	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 23,019 associations by consensus.

Exploration

IFITM2 survival (RNA) · tumor vs normal (RNA) · all IFITM2 data types