Across TCGA patient cohorts, IFITM2 protein abundance is significantly associated with the RNA expression of many other genes, with 7,607 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IFITM2-associated genes across cancer lineages are FAT4, EOGT, and VGLL3. Each is linked with IFITM2 in more than 4 cancer types. Because this analysis shows association rather than direction, both IFITM2-to-partner and partner-to-IFITM2 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IFITM2→partner) and Y-score (partner→IFITM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	FAT4 →	+0.919	+0.561	<.001	<.001	3	5
OV	EOGT →	+1.338	+1.244	<.001	.003	3	4
BRCA	VGLL3 →	+0.798	+0.572	<.001	<.001	3	4
BRCA	MEIS3 →	+1.276	+0.712	<.001	<.001	3	3
BRCA	COL5A1 →	+0.871	+0.449	<.001	<.001	3	3
BRCA	ANGPTL2 →	+0.701	+0.524	.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,607 associations by consensus.

Exploration

IFITM2 survival (RNA) · tumor vs normal (RNA) · all IFITM2 data types