Across TCGA cell cohorts, IFITM2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,141 significant associations in total. BONE shows the largest number of these associations.

The most reproducible IFITM2-associated GO terms across cancer lineages are Response to interferon-alpha, Response to interferon-beta, and Host-mediated suppression of symbiont invasion. Each is linked with IFITM2 in more than 17 cancer types. Because this analysis shows association rather than direction, both IFITM2-to-partner and partner-to-IFITM2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IFITM2→partner) and Y-score (partner→IFITM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Response to interferon-alpha →	+0.180	+4.486	<.001	<.001	3	18
LUNG_NSCLC_LUSC	Response to interferon-beta →	+0.165	+4.064	.001	.001	3	14
BLOOD_Leukemia	Host-mediated suppression of symbiont invasion →	+0.158	+2.087	<.001	<.001	3	14
OESOPHAGUS	Cellular response to interferon-beta →	+0.142	+3.054	<.001	.003	3	12
LUNG_NSCLC_LUSC	Negative regulation of viral genome replication →	+0.166	+3.941	.004	.002	3	11
PANCREAS	Interferon-mediated signaling pathway →	+0.098	+2.408	.002	.006	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,141 associations by consensus.

Exploration

IFITM2 survival (RNA) · tumor vs normal (RNA) · all IFITM2 data types