Across TCGA cell cohorts, IFITM2 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible IFITM2-associated genes across cancer lineages are PROKR2, IL4, and OPN1MW. Each is linked with IFITM2 in more than 1 cancer types. Because this analysis shows association rather than direction, both IFITM2-to-partner and partner-to-IFITM2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IFITM2→partner) and Y-score (partner→IFITM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	PROKR2 →	+0.009	+4.415	<.001	.007	3	1
LARGE_INTESTINE	IL4 →	+0.060	+5.022	<.001	.002	3	1
LARGE_INTESTINE	OPN1MW →	+0.020	+5.022	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Exploration

IFITM2 survival (RNA) · tumor vs normal (RNA) · all IFITM2 data types