Across TCGA patient cohorts, IFITM1 mutation is significantly associated with the RNA expression of many other genes, with 52 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible IFITM1-associated genes across cancer lineages are MTATP6P29, RN7SKP265, and RN7SL321P. Each is linked with IFITM1 in more than 1 cancer types. Because this analysis shows association rather than direction, both IFITM1-to-partner and partner-to-IFITM1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IFITM1→partner) and Y-score (partner→IFITM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MTATP6P29 →	+0.472	+3.718	<.001	.004	3	2
UCEC	RN7SKP265 →	+0.248	+4.727	<.001	.003	3	2
UCEC	RN7SL321P →	+0.525	+4.479	.002	<.001	3	1
COAD	FAM25G →	+0.163	+5.790	<.001	.003	3	1
COAD	RNU6-1013P →	+0.578	+7.142	<.001	<.001	3	1
COAD	RNU6-1068P →	+0.496	+5.602	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 52 associations by consensus.

Exploration

IFITM1 survival (RNA) · tumor vs normal (RNA) · all IFITM1 data types