IFITM1

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, IFITM1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,379 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible IFITM1-associated GO terms across cancer lineages are Response to interferon-beta, Host-mediated suppression of symbiont invasion, and Negative regulation of viral genome replication. Each is linked with IFITM1 in more than 17 cancer types. Because this analysis shows association rather than direction, both IFITM1-to-partner and partner-to-IFITM1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IFITM1→partner) and Y-score (partner→IFITM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_NSCLC_LUSCResponse to interferon-beta →+0.179+4.360.001<.001318
LUNG_NSCLC_LUSCHost-mediated suppression of symbiont invasion →+0.230+3.955<.001<.001318
UPPER_AERODIGESTIVE_TRACTNegative regulation of viral genome replication →+0.195+2.357<.001<.001317
PANCREASNegative regulation of viral process →+0.176+4.106<.001<.001317
BREASTResponse to interferon-alpha →+0.179+3.496<.001<.001316
LARGE_INTESTINEType I interferon-mediated signaling pathway →+0.149+4.207<.001<.001316
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,379 associations by consensus.

Exploration