IFIT5

Across TCGA patient cohorts, IFIT5 mutation is significantly associated with the RNA expression of many other genes, with 2,693 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible IFIT5-associated genes across cancer lineages are RNU6-737P, MIR670, and MIR4802. Each is linked with IFIT5 in more than 1 cancer types. Because this analysis shows association rather than direction, both IFIT5-to-partner and partner-to-IFIT5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-737P grouped by IFIT5-low versus IFIT5-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IFIT5→partner) and Y-score (partner→IFIT5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RNU6-737P →	+0.486	+4.970	<.001	.005	3	2
SKCM	MIR670 →	+0.422	+5.624	<.001	.002	3	2
SKCM	MIR4802 →	+0.657	+5.797	<.001	.001	3	2
BRCA	MIR6853 →	+0.181	+7.473	<.001	.007	3	1
BRCA	RN7SL341P →	+0.096	+5.064	.001	.004	3	1
HNSC	SNORD114-15 →	+0.399	+5.763	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,693 associations by consensus.

RNU6-737P by IFIT5 expression — SKCM

Explore this box plot interactively →