IFIT2

Across TCGA patient cohorts, IFIT2 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,888 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IFIT2-associated proteins across cancer lineages are PSMB6, GBP1, and IFIT1. Each is linked with IFIT2 in more than 9 cancer types. Because this analysis shows association rather than direction, both IFIT2-to-partner and partner-to-IFIT2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IFIT2 versus PSMB6 in OV, with a Pearson correlation of -0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IFIT2→partner) and Y-score (partner→IFIT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PSMB6 →	-0.533	-1.241	<.001	<.001	3	10
BRCA	GBP1 →	+0.820	+1.600	<.001	<.001	3	10
HNSC	IFIT1 →	+1.212	+1.931	<.001	<.001	3	10
HNSC	IFIT3 →	+1.388	+1.979	<.001	<.001	3	10
HNSC	TRIM21 →	+0.482	+1.425	<.001	<.001	3	10
OV	APOL2 →	+0.885	+1.287	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,888 associations by consensus.

IFIT2 vs PSMB6 — OV

Explore this scatter interactively →