IFIT2

Across TCGA patient cohorts, IFIT2 protein abundance is significantly associated with the RNA expression of many other genes, with 10,024 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IFIT2-associated genes across cancer lineages are OAS2, IFIH1, and STAT1. Each is linked with IFIT2 in more than 9 cancer types. Because this analysis shows association rather than direction, both IFIT2-to-partner and partner-to-IFIT2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IFIT2 versus OAS2 in OV, with a Pearson correlation of 0.76.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IFIT2→partner) and Y-score (partner→IFIT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	OAS2 →	+1.662	+0.811	<.001	<.001	3	10
HNSC	IFIH1 →	+1.434	+1.334	<.001	<.001	3	10
HNSC	STAT1 →	+1.067	+1.045	<.001	<.001	3	10
HNSC	GBP1 →	+1.249	+0.947	<.001	<.001	3	10
HNSC	IFIT3 →	+2.201	+1.352	<.001	<.001	3	10
BRCA	IFI6 →	+2.180	+0.762	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,024 associations by consensus.

IFIT2 vs OAS2 — OV

Explore this scatter interactively →