Across TCGA patient cohorts, IFIT1 RNA expression is significantly associated with the RNA expression of many other genes, with 17,000 significant associations in total. UVM shows the largest number of these associations.

The most reproducible IFIT1-associated genes across cancer lineages are DDX58, OAS3, and IFIH1. Each is linked with IFIT1 in more than 33 cancer types. Because this analysis shows association rather than direction, both IFIT1-to-partner and partner-to-IFIT1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IFIT1→partner) and Y-score (partner→IFIT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	DDX58 →	+1.700	+2.531	<.001	<.001	3	34
CHOL	OAS3 →	+2.155	+2.640	<.001	<.001	3	34
BLCA	IFIH1 →	+1.756	+2.517	<.001	<.001	3	34
BLCA	IFIT3 →	+2.702	+2.773	<.001	<.001	3	34
BLCA	IFIT2 →	+2.235	+2.666	<.001	<.001	3	34
HNSC	RSAD2 →	+2.525	+2.709	<.001	<.001	3	34

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,000 associations by consensus.

Exploration

IFIT1 survival (RNA) · tumor vs normal (RNA) · all IFIT1 data types