Across TCGA patient cohorts, IFIT1 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,760 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IFIT1-associated proteins across cancer lineages are IFIT2, IFIT3, and IFIT5. Each is linked with IFIT1 in more than 9 cancer types. Because this analysis shows association rather than direction, both IFIT1-to-partner and partner-to-IFIT1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IFIT1→partner) and Y-score (partner→IFIT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	IFIT2 →	+1.319	+2.180	<.001	<.001	3	10
HNSC	IFIT3 →	+1.387	+2.200	<.001	<.001	3	10
HNSC	IFIT5 →	+0.561	+1.413	<.001	<.001	3	10
HNSC	UBE2L6 →	+0.668	+1.667	<.001	<.001	3	9
COAD	XAF1 →	+0.990	+1.531	.001	.002	3	9
HNSC	MX2 →	+1.054	+2.253	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,760 associations by consensus.

Exploration

IFIT1 survival (RNA) · tumor vs normal (RNA) · all IFIT1 data types