Across TCGA patient cohorts, IFIT1 protein abundance is significantly associated with the RNA expression of many other genes, with 8,361 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible IFIT1-associated genes across cancer lineages are DDX58, OAS3, and OAS2. Each is linked with IFIT1 in more than 9 cancer types. Because this analysis shows association rather than direction, both IFIT1-to-partner and partner-to-IFIT1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IFIT1→partner) and Y-score (partner→IFIT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	DDX58 →	+1.365	+1.149	<.001	<.001	3	10
OV	OAS3 →	+1.507	+0.891	<.001	<.001	3	10
OV	OAS2 →	+1.727	+0.953	<.001	<.001	3	10
HNSC	IFIH1 →	+1.346	+1.168	<.001	<.001	3	10
OV	STAT1 →	+1.023	+0.768	<.001	<.001	3	10
HNSC	IFIT3 →	+2.183	+1.242	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,361 associations by consensus.

Exploration

IFIT1 survival (RNA) · tumor vs normal (RNA) · all IFIT1 data types