IFIT1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, IFIT1 mutation is significantly associated with the RNA expression of many other genes, with 4,154 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible IFIT1-associated genes across cancer lineages are MIR4662B, PSAT1P4, and RPL18P1. Each is linked with IFIT1 in more than 1 cancer types. Because this analysis shows association rather than direction, both IFIT1-to-partner and partner-to-IFIT1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IFIT1→partner) and Y-score (partner→IFIT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLCAMIR4662B →+0.657+5.329<.001.00632
COADPSAT1P4 →+0.334+3.463<.001.00632
COADRPL18P1 →+0.282+3.957<.001.00332
COADGAPDHP56 →+0.102+4.017.007.00332
LUSCSNORA36C →+0.274+5.038<.001.00932
BLCARNA5SP237 →+0.453+5.588<.001.00432
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,154 associations by consensus.

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