IFIT1

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, IFIT1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,865 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible IFIT1-associated GO terms across cancer lineages are Negative regulation of viral genome replication, Negative regulation of viral process, and Defense response to virus. Each is linked with IFIT1 in more than 18 cancer types. Because this analysis shows association rather than direction, both IFIT1-to-partner and partner-to-IFIT1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IFIT1→partner) and Y-score (partner→IFIT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UPPER_AERODIGESTIVE_TRACTNegative regulation of viral genome replication →+0.216+3.222<.001<.001319
KIDNEYNegative regulation of viral process →+0.185+3.072.004<.001318
UPPER_AERODIGESTIVE_TRACTDefense response to virus →+0.092+3.112<.001<.001318
LUNG_NSCLC_LUSCRegulation of viral process →+0.111+2.918.001<.001317
BREASTAntiviral innate immune response →+0.100+3.127<.001<.001317
BREASTResponse to interferon-alpha →+0.187+3.434<.001<.001317
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,865 associations by consensus.

Exploration