IFI35

Across TCGA patient cohorts, IFI35 protein abundance is significantly associated with the RNA expression of many other genes, with 15,416 significant associations in total. GBM shows the largest number of these associations.

The most reproducible IFI35-associated genes across cancer lineages are OAS2, IFIH1, and CD80. Each is linked with IFI35 in more than 9 cancer types. Because this analysis shows association rather than direction, both IFI35-to-partner and partner-to-IFI35 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IFI35 versus OAS2 in OV, with a Pearson correlation of 0.69.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IFI35→partner) and Y-score (partner→IFI35) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	OAS2 →	+1.620	+0.453	<.001	<.001	3	10
HNSC	IFIH1 →	+1.114	+0.524	<.001	<.001	3	10
HNSC	CD80 →	+1.086	+0.646	<.001	<.001	3	10
HNSC	NMI →	+0.789	+0.478	<.001	<.001	3	10
OV	ZBP1 →	+0.830	+0.407	<.001	<.001	3	10
HNSC	EPSTI1 →	+1.196	+0.535	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,416 associations by consensus.

IFI35 vs OAS2 — OV

Explore this scatter interactively →