IFI35

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, IFI35 mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible IFI35-associated genes across cancer lineages are Epithelial cells and Plasma cells. Each is linked with IFI35 in more than 1 cancer types. Because this analysis shows association rather than direction, both IFI35-to-partner and partner-to-IFI35 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Epithelial cells grouped by IFI35-low versus IFI35-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IFI35→partner) and Y-score (partner→IFI35) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECEpithelial cells →-0.091-2.991.011.03632
UCECPlasma cells →-0.024-3.416.027.00511
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Epithelial cells by IFI35 expression — UCEC

Box plot of Epithelial cells in IFI35-low vs IFI35-high samples in UCEC.

Explore this box plot interactively →

Exploration