Across TCGA patient cohorts, IFI30 mutation is significantly associated with the total protein of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible IFI30-associated genes across cancer lineages are CD20, Lck, and MAPK_pT202_Y204. Each is linked with IFI30 in more than 1 cancer types. Because this analysis shows association rather than direction, both IFI30-to-partner and partner-to-IFI30 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IFI30→partner) and Y-score (partner→IFI30) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CD20 →	+0.170	+3.020	.025	.019	3	1
UCEC	Lck →	+0.288	+3.000	.013	.037	1	1
UCEC	MAPK_pT202_Y204 →	-0.659	-3.000	.015	.037	1	1
UCEC	p38-MAPK_pT180_Y182 →	-0.755	-2.986	.003	.037	1	1
UCEC	Rad50 →	-0.390	-3.000	.005	.037	1	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Exploration

IFI30 survival (RNA) · tumor vs normal (RNA) · all IFI30 data types