IFI27L2

Across TCGA patient cohorts, IFI27L2 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,743 significant associations in total. GBM shows the largest number of these associations.

The most reproducible IFI27L2-associated proteins across cancer lineages are CDC42BPB, AHNAK2_S842, and NFKB1. Each is linked with IFI27L2 in more than 4 cancer types. Because this analysis shows association rather than direction, both IFI27L2-to-partner and partner-to-IFI27L2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IFI27L2 versus CDC42BPB in HNSC, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IFI27L2→partner) and Y-score (partner→IFI27L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CDC42BPB →	+0.225	+0.889	<.001	<.001	3	5
LSCC	AHNAK2_S842 →	+1.548	+0.708	<.001	<.001	3	5
OV	NFKB1 →	+0.359	+0.974	<.001	<.001	3	5
BRCA	DAP3 →	-0.502	-0.901	<.001	<.001	3	4
GBM	S100A10 →	+0.697	+0.562	<.001	<.001	3	4
BRCA	BMP2K →	+0.222	+1.028	.004	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,743 associations by consensus.

IFI27L2 vs CDC42BPB — HNSC

Explore this scatter interactively →