IFI27L2

Across TCGA patient cohorts, IFI27L2 protein abundance is significantly associated with the RNA expression of many other genes, with 3,187 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IFI27L2-associated genes across cancer lineages are TMEM183A, SLN, and PCDHGB4. Each is linked with IFI27L2 in more than 1 cancer types. Because this analysis shows association rather than direction, both IFI27L2-to-partner and partner-to-IFI27L2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IFI27L2 versus TMEM183A in LUAD, with a Pearson correlation of -0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IFI27L2→partner) and Y-score (partner→IFI27L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	TMEM183A →	-0.304	-0.432	.008	.002	3	2
LUAD	SLN →	-0.732	-0.423	<.001	.003	3	2
LUAD	PCDHGB4 →	+0.760	+0.468	.004	.002	3	2
CCRCC	PCDHGA4 →	+2.045	+0.647	.004	.009	3	2
UCEC	NT5C2 →	-0.589	-0.619	.008	.003	3	2
UCEC	TJP3 →	-1.326	-0.635	.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,187 associations by consensus.

IFI27L2 vs TMEM183A — LUAD

Explore this scatter interactively →