IFI27L2

Across TCGA patient cohorts, IFI27L2 mutation is significantly associated with the RNA expression of many other genes, with 595 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible IFI27L2-associated genes across cancer lineages are UBL5P4, CGB2, and BPIFA3. Each is linked with IFI27L2 in more than 1 cancer types. Because this analysis shows association rather than direction, both IFI27L2-to-partner and partner-to-IFI27L2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, UBL5P4 grouped by IFI27L2-low versus IFI27L2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IFI27L2→partner) and Y-score (partner→IFI27L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	UBL5P4 →	+0.294	+2.957	<.001	.001	3	2
READ	CGB2 →	+1.015	+5.219	<.001	.006	3	1
READ	BPIFA3 →	+0.022	+5.653	<.001	.003	3	1
READ	RNU6-254P →	+0.573	+5.039	<.001	.008	3	1
READ	RNA5SP48 →	+0.372	+5.653	<.001	.003	3	1
READ	RNU6-800P →	+0.466	+5.039	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 595 associations by consensus.

UBL5P4 by IFI27L2 expression — UCEC

Explore this box plot interactively →