IFI27L2

Across TCGA cell cohorts, IFI27L2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,290 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible IFI27L2-associated GO terms across cancer lineages are Apoptotic signaling pathway, Positive regulation of extracellular matrix organization, and Intrinsic apoptotic signaling pathway. Each is linked with IFI27L2 in more than 12 cancer types. Because this analysis shows association rather than direction, both IFI27L2-to-partner and partner-to-IFI27L2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Apoptotic signaling pathway grouped by IFI27L2-low versus IFI27L2-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IFI27L2→partner) and Y-score (partner→IFI27L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Apoptotic signaling pathway →	+0.056	+1.858	<.001	.001	3	13
LIVER	Positive regulation of extracellular matrix organization →	+0.155	+2.891	<.001	<.001	3	12
BONE	Intrinsic apoptotic signaling pathway →	+0.082	+1.820	<.001	<.001	3	12
BONE	Regulation of reactive oxygen species metabolic process →	+0.083	+1.562	<.001	<.001	3	11
LARGE_INTESTINE	Regulation of release of cytochrome c from mitochondria →	+0.111	+1.389	.001	.004	2	12
BONE	Response to acetaldehyde →	+0.267	+1.681	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,290 associations by consensus.

Apoptotic signaling pathway by IFI27L2 expression — BONE

Explore this box plot interactively →