IFI27

Across TCGA patient cohorts, IFI27 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,169 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IFI27-associated proteins across cancer lineages are UBE2L6, IFIT1, and IFIT3. Each is linked with IFI27 in more than 9 cancer types. Because this analysis shows association rather than direction, both IFI27-to-partner and partner-to-IFI27 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IFI27 versus UBE2L6 in BRCA, with a Pearson correlation of 0.63.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IFI27→partner) and Y-score (partner→IFI27) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	UBE2L6 →	+0.735	+2.001	<.001	<.001	3	10
LSCC	IFIT1 →	+1.014	+1.974	<.001	<.001	3	10
LSCC	IFIT3 →	+1.042	+1.959	<.001	<.001	3	10
BRCA	IRF9 →	+0.543	+1.962	<.001	<.001	3	10
LSCC	ISG15 →	+1.053	+1.742	<.001	<.001	3	10
LSCC	OAS2 →	+1.110	+1.924	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,169 associations by consensus.

IFI27 vs UBE2L6 — BRCA

Explore this scatter interactively →