IFI27

Across TCGA patient cohorts, IFI27 protein abundance is significantly associated with the RNA expression of many other genes, with 5,341 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IFI27-associated genes across cancer lineages are OAS3, OAS2, and IFI6. Each is linked with IFI27 in more than 3 cancer types. Because this analysis shows association rather than direction, both IFI27-to-partner and partner-to-IFI27 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IFI27 versus OAS3 in LSCC, with a Pearson correlation of 0.62.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IFI27→partner) and Y-score (partner→IFI27) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	OAS3 →	+1.116	+0.653	<.001	<.001	3	4
LSCC	OAS2 →	+1.434	+0.790	<.001	<.001	3	4
BRCA	IFI6 →	+1.625	+0.702	<.001	<.001	3	4
LSCC	DDX60 →	+1.150	+0.817	<.001	<.001	3	4
LUAD	ETV7 →	+1.095	+0.482	<.001	<.001	3	3
HNSC	RBFA →	-0.529	-0.647	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,341 associations by consensus.

IFI27 vs OAS3 — LSCC

Explore this scatter interactively →