IFI16

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, IFI16 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,903 significant associations in total. GBM shows the largest number of these associations.

The most reproducible IFI16-associated proteins across cancer lineages are IFI16_S106, STAT2, and IFI35. Each is linked with IFI16 in more than 9 cancer types. Because this analysis shows association rather than direction, both IFI16-to-partner and partner-to-IFI16 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IFI16 versus IFI16_S106 in BRCA, with a Pearson correlation of 0.57.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IFI16→partner) and Y-score (partner→IFI16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCAIFI16_S106 →+1.052+1.260<.001<.001310
OVSTAT2 →+0.495+0.992<.001<.00139
BRCAIFI35 →+0.560+1.360<.001<.00139
BRCAUBE2L6 →+0.675+1.136.001<.00139
LSCCMX2 →+0.727+0.566<.001.00939
OVNMI →+0.640+1.344<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 14,903 associations by consensus.

IFI16 vs IFI16_S106 — BRCA

Per-sample scatter of IFI16 vs IFI16_S106 in BRCA (Pearson r = 0.57).

Explore this scatter interactively →

Exploration