IFI16

Across TCGA cell cohorts, IFI16 RNA expression is significantly associated with the RNA expression of many other genes, with 10,844 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible IFI16-associated genes across cancer lineages are IFI44, SAMD9L, and CARD16. Each is linked with IFI16 in more than 12 cancer types. Because this analysis shows association rather than direction, both IFI16-to-partner and partner-to-IFI16 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IFI16 versus IFI44 in BREAST, with a Pearson correlation of 0.73.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IFI16→partner) and Y-score (partner→IFI16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	IFI44 →	+3.430	+2.941	<.001	<.001	3	13
LIVER	SAMD9L →	+1.830	+3.824	<.001	<.001	3	12
LIVER	CARD16 →	+3.051	+4.353	<.001	<.001	3	11
LUNG_NSCLC_LUSC	SAMD9 →	+2.304	+2.503	<.001	<.001	3	11
LUNG_SCLC	SP100 →	+2.790	+2.895	<.001	<.001	3	11
SOFT_TISSUE	GBP3 →	+2.977	+4.191	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,844 associations by consensus.

IFI16 vs IFI44 — BREAST

Explore this scatter interactively →