IFFO2

Across TCGA patient cohorts, IFFO2 protein abundance is significantly associated with the RNA expression of many other genes, with 11,521 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible IFFO2-associated genes across cancer lineages are GSDMC, GPR89A, and RPRD1A. Each is linked with IFFO2 in more than 3 cancer types. Because this analysis shows association rather than direction, both IFFO2-to-partner and partner-to-IFFO2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IFFO2 versus GSDMC in HNSC, with a Pearson correlation of 0.46.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IFFO2→partner) and Y-score (partner→IFFO2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	GSDMC →	+2.198	+1.174	<.001	<.001	3	4
UCEC	GPR89A →	-0.592	-0.520	<.001	.002	3	3
HNSC	RPRD1A →	-0.471	-0.754	.003	<.001	3	3
CCRCC	TXNDC16 →	-0.707	-0.457	.005	.008	3	3
PDAC	DBP →	-0.650	-0.562	.004	.006	3	3
UCEC	PRKAB2 →	-0.610	-0.476	<.001	.007	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,521 associations by consensus.

IFFO2 vs GSDMC — HNSC

Explore this scatter interactively →