IFFO2

Across TCGA patient cohorts, IFFO2 protein abundance is significantly associated with the protein abundance of many other proteins, with 13,833 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible IFFO2-associated proteins across cancer lineages are FAM83H_S523, FAM83H_S892, and MAP7D1_S254. Each is linked with IFFO2 in more than 4 cancer types. Because this analysis shows association rather than direction, both IFFO2-to-partner and partner-to-IFFO2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IFFO2 versus FAM83H_S523 in BRCA, with a Pearson correlation of 0.46.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IFFO2→partner) and Y-score (partner→IFFO2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	FAM83H_S523 →	+1.142	+0.732	<.001	<.001	3	4
LSCC	FAM83H_S892 →	+1.217	+0.708	<.001	<.001	3	4
HNSC	MAP7D1_S254 →	+0.735	+0.697	<.001	<.001	3	4
HNSC	BAG3 →	+0.510	+0.919	<.001	<.001	3	3
HNSC	ACSS1 →	-0.724	-1.047	<.001	<.001	3	3
HNSC	BICD2 →	+0.616	+0.862	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,833 associations by consensus.

IFFO2 vs FAM83H_S523 — BRCA

Explore this scatter interactively →