IFFO2

Across TCGA patient cohorts, IFFO2 mutation is significantly associated with the total protein of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible IFFO2-associated genes across cancer lineages are cIAP and beta-Catenin. Each is linked with IFFO2 in more than 1 cancer types. Because this analysis shows association rather than direction, both IFFO2-to-partner and partner-to-IFFO2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, cIAP grouped by IFFO2-low versus IFFO2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IFFO2→partner) and Y-score (partner→IFFO2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	cIAP →	+0.161	+3.026	.043	.019	3	1
UCEC	beta-Catenin →	+0.584	+3.000	.046	.037	1	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

cIAP by IFFO2 expression — UCEC

Explore this box plot interactively →