Across TCGA patient cohorts, IER5L RNA expression is significantly associated with the protein abundance of many other proteins, with 10,959 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible IER5L-associated proteins across cancer lineages are VAV2, LOXL2, and NTMT1. Each is linked with IER5L in more than 5 cancer types. Because this analysis shows association rather than direction, both IER5L-to-partner and partner-to-IER5L results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IER5L→partner) and Y-score (partner→IER5L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	VAV2 →	+0.492	+0.810	<.001	<.001	3	5
GBM	LOXL2 →	+0.639	+0.729	.001	.004	3	5
HNSC	NTMT1 →	+0.241	+0.549	.001	.003	3	5
COAD	RAB31 →	+0.514	+0.848	<.001	<.001	3	5
COAD	PLAU →	+0.767	+0.957	.007	.001	2	6
GBM	COL12A1 →	+0.765	+0.688	.003	.003	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,959 associations by consensus.

Exploration

IER5L survival (RNA) · tumor vs normal (RNA) · all IER5L data types