IER5

Across TCGA patient cohorts, IER5 mutation is significantly associated with the immune_cell of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible IER5-associated genes across cancer lineages are CMP, Neurons, and Th2 cells. Each is linked with IER5 in more than 1 cancer types. Because this analysis shows association rather than direction, both IER5-to-partner and partner-to-IER5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CMP grouped by IER5-low versus IER5-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IER5→partner) and Y-score (partner→IER5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CMP →	-0.033	-3.000	.026	.036	3	1
UCEC	Neurons →	-0.020	-3.281	.029	.010	3	1
UCEC	Th2 cells →	+0.261	+2.818	.002	.035	3	1
UCEC	CD8+ naive T-cells →	+0.028	+3.016	.029	.019	2	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

CMP by IER5 expression — UCEC

Explore this box plot interactively →