IER5

Across TCGA cell cohorts, IER5 RNA expression is significantly associated with the RNA expression of many other genes, with 6,773 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible IER5-associated genes across cancer lineages are PHLDA3, PLK3, and PLEKHF1. Each is linked with IER5 in more than 9 cancer types. Because this analysis shows association rather than direction, both IER5-to-partner and partner-to-IER5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IER5 versus PHLDA3 in LUNG_NSCLC_LUSC, with a Pearson correlation of 0.52.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IER5→partner) and Y-score (partner→IER5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	PHLDA3 →	+2.747	+1.186	.002	<.001	2	10
URINARY_TRACT	PLK3 →	+1.692	+1.320	<.001	<.001	3	9
BLOOD_Lymphoma	PLEKHF1 →	+1.557	+1.682	<.001	<.001	3	8
BLOOD_Lymphoma	CDKN1A →	+2.999	+1.503	<.001	<.001	3	8
BLOOD_Myeloma	STX6 →	+0.726	+1.065	.007	.005	1	10
OESOPHAGUS	IKBKE →	+1.472	+1.543	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,773 associations by consensus.

IER5 vs PHLDA3 — LUNG_NSCLC_LUSC

Explore this scatter interactively →