IER3IP1

Across TCGA patient cohorts, IER3IP1 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,566 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IER3IP1-associated proteins across cancer lineages are SMAD4, NEDD4L, and NARS1. Each is linked with IER3IP1 in more than 7 cancer types. Because this analysis shows association rather than direction, both IER3IP1-to-partner and partner-to-IER3IP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IER3IP1 versus SMAD4 in OV, with a Pearson correlation of 0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IER3IP1→partner) and Y-score (partner→IER3IP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	SMAD4 →	+0.329	+0.620	<.001	.001	3	8
LSCC	NEDD4L →	+0.419	+0.824	<.001	<.001	3	6
COAD	NARS1 →	+0.262	+0.575	<.001	<.001	3	5
COAD	VPS4B →	+0.306	+0.735	<.001	<.001	3	5
OV	RPRD1A →	+0.588	+0.721	<.001	<.001	3	5
HNSC	SMAD2 →	+0.331	+0.895	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,566 associations by consensus.

IER3IP1 vs SMAD4 — OV

Explore this scatter interactively →