IER3IP1

Across TCGA patient cohorts, IER3IP1 protein abundance is significantly associated with the RNA expression of many other genes, with 97 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible IER3IP1-associated genes across cancer lineages are NKG7, WWP1, and NDUFAF4. Each is linked with IER3IP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both IER3IP1-to-partner and partner-to-IER3IP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IER3IP1 versus NKG7 in CCRCC, with a Pearson correlation of 0.81.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IER3IP1→partner) and Y-score (partner→IER3IP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	NKG7 →	+1.607	+0.429	<.001	.001	3	1
CCRCC	WWP1 →	-0.710	-0.476	.001	.004	3	1
CCRCC	NDUFAF4 →	+0.560	+0.290	.005	.005	3	1
CCRCC	GNG13 →	+0.150	+0.303	.001	.004	3	1
CCRCC	AAR2 →	+0.232	+0.327	.004	.007	3	1
CCRCC	ITGB7 →	+0.547	+0.442	.002	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 97 associations by consensus.

IER3IP1 vs NKG7 — CCRCC

Explore this scatter interactively →