IER3IP1

Across TCGA cell cohorts, IER3IP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,958 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible IER3IP1-associated GO terms across cancer lineages are Establishment of meiotic spindle orientation, Positive regulation of extracellular matrix constituent secretion, and DNA synthesis involved in DNA replication. Each is linked with IER3IP1 in more than 12 cancer types. Because this analysis shows association rather than direction, both IER3IP1-to-partner and partner-to-IER3IP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Establishment of meiotic spindle orientation grouped by IER3IP1-low versus IER3IP1-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IER3IP1→partner) and Y-score (partner→IER3IP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Establishment of meiotic spindle orientation →	+0.205	+1.335	.001	<.001	2	13
LUNG_NSCLC_LUAD	Positive regulation of extracellular matrix constituent secretion →	+0.825	+0.663	<.001	<.001	3	11
LUNG_SCLC	DNA synthesis involved in DNA replication →	+0.099	+0.557	<.001	.003	3	10
LUNG_SCLC	Translesion synthesis →	+0.098	+0.600	<.001	.001	3	10
LUNG_SCLC	DNA damage tolerance →	+0.090	+0.594	<.001	.001	3	10
CNS	Negative regulation of cell cycle checkpoint →	+0.122	+0.426	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,958 associations by consensus.

Establishment of meiotic spindle orientation by IER3IP1 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →