IER3

Across TCGA patient cohorts, IER3 protein abundance is significantly associated with the RNA expression of many other genes, with 1,192 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible IER3-associated genes across cancer lineages are ATF3, JUN, and MICALL1. Each is linked with IER3 in more than 1 cancer types. Because this analysis shows association rather than direction, both IER3-to-partner and partner-to-IER3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IER3 versus ATF3 in LUAD, with a Pearson correlation of 0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IER3→partner) and Y-score (partner→IER3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	ATF3 →	+0.974	+0.577	.004	.001	3	2
LUAD	JUN →	+0.738	+0.705	.002	<.001	3	2
UCEC	MICALL1 →	-0.661	-0.470	.004	.002	3	1
UCEC	CLEC2B →	+0.549	+0.343	.003	<.001	3	1
UCEC	KCNQ4 →	-0.576	-0.421	.005	.001	3	1
UCEC	CIT →	-0.458	-0.337	.006	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,192 associations by consensus.

IER3 vs ATF3 — LUAD

Explore this scatter interactively →