Across TCGA patient cohorts, IDO2 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,373 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible IDO2-associated proteins across cancer lineages are ADA2, SASH3, and MYO1G. Each is linked with IDO2 in more than 7 cancer types. Because this analysis shows association rather than direction, both IDO2-to-partner and partner-to-IDO2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IDO2→partner) and Y-score (partner→IDO2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ADA2 →	+0.684	+1.210	<.001	<.001	3	8
UCEC	SASH3 →	+0.495	+0.976	<.001	.001	3	7
BRCA	MYO1G →	+0.638	+0.401	<.001	.006	3	7
HNSC	WAS →	+0.531	+0.589	<.001	<.001	3	7
HNSC	DOCK2 →	+0.563	+0.586	<.001	<.001	3	7
UCEC	FYB1 →	+0.657	+1.121	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,373 associations by consensus.

Exploration

IDO2 survival (RNA) · tumor vs normal (RNA) · all IDO2 data types