IDO2

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, IDO2 RNA expression is significantly associated with the go_rna of many other GO terms, with 318 significant associations in total. BONE shows the largest number of these associations.

The most reproducible IDO2-associated GO terms across cancer lineages are Regulation of RNA splicing, Regulation of mRNA processing, and Iron ion transport. Each is linked with IDO2 in more than 3 cancer types. Because this analysis shows association rather than direction, both IDO2-to-partner and partner-to-IDO2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IDO2→partner) and Y-score (partner→IDO2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BONERegulation of RNA splicing →+0.073+0.023<.001.00233
BONERegulation of mRNA processing →+0.067+0.026<.001.00324
UPPER_AERODIGESTIVE_TRACTIron ion transport →+0.087+0.085<.001.00233
UPPER_AERODIGESTIVE_TRACTRegulation of protein ubiquitination →+0.038+0.078.001.00533
SKINRegulation of DNA-templated transcription elongation →+0.038+0.030.001.00533
SKINPositive regulation of translation →+0.049+0.029<.001.00833
Each partner links to its Q-omics profile. Showing the 6 strongest of 318 associations by consensus.

Exploration