Across TCGA cell cohorts, IDO2 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible IDO2-associated genes across cancer lineages are KLHL40, PRAMEF27, and NCR2. Each is linked with IDO2 in more than 1 cancer types. Because this analysis shows association rather than direction, both IDO2-to-partner and partner-to-IDO2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IDO2→partner) and Y-score (partner→IDO2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	KLHL40 →	+0.006	+4.273	<.001	.006	3	1
SKIN	PRAMEF27 →	+0.040	+4.095	<.001	.009	3	1
SKIN	NCR2 →	+0.015	+5.022	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Exploration

IDO2 survival (RNA) · tumor vs normal (RNA) · all IDO2 data types