IDO1

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, IDO1 protein abundance is significantly associated with the protein abundance of many other proteins, with 12,853 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible IDO1-associated proteins across cancer lineages are GBP1, GBP4, and GBP5. Each is linked with IDO1 in more than 8 cancer types. Because this analysis shows association rather than direction, both IDO1-to-partner and partner-to-IDO1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IDO1 versus GBP1 in HNSC, with a Pearson correlation of 0.82.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IDO1→partner) and Y-score (partner→IDO1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCGBP1 →+1.149+1.449<.001<.00139
HNSCGBP4 →+1.003+1.446<.001<.00139
HNSCGBP5 →+1.345+1.477<.001<.00139
HNSCPSMB10 →+0.626+1.310<.001<.00139
HNSCPSMB9 →+0.516+1.259<.001<.00139
COADPSME2 →+0.528+1.100<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 12,853 associations by consensus.

IDO1 vs GBP1 — HNSC

Per-sample scatter of IDO1 vs GBP1 in HNSC (Pearson r = 0.82).

Explore this scatter interactively →

Exploration