IDI2

Across TCGA patient cohorts, IDI2 mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible IDI2-associated genes across cancer lineages are Th2 cells and Epithelial cells. Each is linked with IDI2 in more than 1 cancer types. Because this analysis shows association rather than direction, both IDI2-to-partner and partner-to-IDI2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Th2 cells grouped by IDI2-low versus IDI2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IDI2→partner) and Y-score (partner→IDI2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Th2 cells →	+0.294	+2.815	.004	.036	3	1
UCEC	Epithelial cells →	-0.137	-3.000	<.001	.037	1	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Th2 cells by IDI2 expression — UCEC

Explore this box plot interactively →