IDI2

Across TCGA cell cohorts, IDI2 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. URINARY_TRACT shows the largest number of these associations.

The most reproducible IDI2-associated genes across cancer lineages are OR1L4 and HTR3B. Each is linked with IDI2 in more than 1 cancer types. Because this analysis shows association rather than direction, both IDI2-to-partner and partner-to-IDI2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR1L4 grouped by IDI2-low versus IDI2-high in URINARY_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IDI2→partner) and Y-score (partner→IDI2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	OR1L4 →	+0.060	+4.087	<.001	.009	3	1
URINARY_TRACT	HTR3B →	+0.034	+4.584	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

OR1L4 by IDI2 expression — URINARY_TRACT

Explore this box plot interactively →