IDH3A

Across TCGA patient cohorts, IDH3A RNA expression is significantly associated with the protein abundance of many other proteins, with 10,469 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IDH3A-associated proteins across cancer lineages are IDH3B, DNAJA4, and CLK3_S157. Each is linked with IDH3A in more than 5 cancer types. Because this analysis shows association rather than direction, both IDH3A-to-partner and partner-to-IDH3A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IDH3A versus IDH3B in OV, with a Pearson correlation of 0.56.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IDH3A→partner) and Y-score (partner→IDH3A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	IDH3B →	+0.524	+0.961	<.001	<.001	3	6
HNSC	DNAJA4 →	+0.572	+0.319	<.001	.005	3	5
OV	CLK3_S157 →	+0.554	+0.452	.003	.002	3	4
LUAD	EIF3J →	+0.269	+0.365	<.001	<.001	3	4
OV	IDH3G →	+0.303	+0.518	<.001	<.001	3	4
PDAC	AKAP13_S983 →	+0.798	+0.275	.001	.005	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,469 associations by consensus.

IDH3A vs IDH3B — OV

Explore this scatter interactively →