ID3

Across TCGA cell cohorts, ID3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,889 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ID3-associated GO terms across cancer lineages are Mitotic chromosome condensation, Left ventricular cardiac muscle tissue morphogenesis, and Mitotic DNA damage checkpoint signaling. Each is linked with ID3 in more than 8 cancer types. Because this analysis shows association rather than direction, both ID3-to-partner and partner-to-ID3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitotic chromosome condensation grouped by ID3-low versus ID3-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ID3→partner) and Y-score (partner→ID3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Mitotic chromosome condensation →	+0.092	+1.362	.002	<.001	3	9
PANCREAS	Left ventricular cardiac muscle tissue morphogenesis →	+1.049	+2.430	<.001	.001	3	9
BLOOD_Lymphoma	Mitotic DNA damage checkpoint signaling →	+0.069	+2.862	<.001	<.001	3	8
LUNG_NSCLC_LUSC	Maintenance of blood-brain barrier →	-0.220	-2.493	.001	<.001	3	8
BLOOD_Leukemia	Disaccharide transport →	-0.969	-2.767	<.001	<.001	3	8
BLOOD_Leukemia	Sucrose transport →	-0.969	-2.767	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,889 associations by consensus.

Mitotic chromosome condensation by ID3 expression — SOFT_TISSUE

Explore this box plot interactively →