ID2

Across TCGA patient cohorts, ID2 mutation is significantly associated with the RNA expression of many other genes, with 188 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ID2-associated genes across cancer lineages are LINC02559, RNA5SP198, and RNA5SP205. Each is linked with ID2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ID2-to-partner and partner-to-ID2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC02559 grouped by ID2-low versus ID2-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ID2→partner) and Y-score (partner→ID2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	LINC02559 →	+1.329	+5.342	<.001	.002	3	2
CESC	RNA5SP198 →	+0.284	+5.144	<.001	.003	3	2
UCEC	RNA5SP205 →	+0.377	+3.437	<.001	.004	3	2
BRCA	MIR3118-3 →	+0.372	+8.471	<.001	.005	3	1
CESC	FAM96AP1 →	+0.089	+6.584	<.001	<.001	3	1
CESC	HS6ST2-AS1 →	+0.135	+4.193	.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 188 associations by consensus.

LINC02559 by ID2 expression — CESC

Explore this box plot interactively →