ID2

Across TCGA cell cohorts, ID2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,626 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ID2-associated GO terms across cancer lineages are Negative regulation of B cell differentiation, Bundle of His development, and His-Purkinje system development. Each is linked with ID2 in more than 19 cancer types. Because this analysis shows association rather than direction, both ID2-to-partner and partner-to-ID2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of B cell differentiation grouped by ID2-low versus ID2-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ID2→partner) and Y-score (partner→ID2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Negative regulation of B cell differentiation →	+1.256	+2.857	<.001	<.001	3	20
PANCREAS	Bundle of His development →	+1.240	+3.039	<.001	<.001	3	18
BLOOD_Lymphoma	His-Purkinje system development →	+0.765	+2.504	<.001	<.001	3	16
BLOOD_Leukemia	Mammary gland alveolus development →	+0.366	+2.474	<.001	<.001	3	16
BLOOD_Leukemia	Mammary gland lobule development →	+0.366	+2.474	<.001	<.001	3	16
BLOOD_Leukemia	Membranous septum morphogenesis →	+0.485	+2.034	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,626 associations by consensus.

Negative regulation of B cell differentiation by ID2 expression — PANCREAS

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