ID1

Across TCGA patient cohorts, ID1 protein abundance is significantly associated with the RNA expression of many other genes, with 2,961 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible ID1-associated genes across cancer lineages are TRPC4, NT5C1A, and RNASE3. Each is linked with ID1 in more than 2 cancer types. Because this analysis shows association rather than direction, both ID1-to-partner and partner-to-ID1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ID1 versus TRPC4 in GBM, with a Pearson correlation of 0.21.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ID1→partner) and Y-score (partner→ID1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	TRPC4 →	+0.618	+0.386	.006	.002	3	3
LUAD	NT5C1A →	-1.082	-0.370	.006	<.001	3	2
UCEC	RNASE3 →	+0.678	+0.251	.009	.005	3	2
UCEC	ALOX15P2 →	-0.726	-0.401	.001	<.001	3	2
LUAD	UPK3A →	-0.717	-0.331	.008	.004	3	2
LUAD	CACNA1F →	-0.446	-0.326	.008	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,961 associations by consensus.

ID1 vs TRPC4 — GBM

Explore this scatter interactively →