ID1

Across TCGA patient cohorts, ID1 mutation is significantly associated with the RNA expression of many other genes, with 166 significant associations in total. BLCA shows the largest number of these associations.

The most reproducible ID1-associated genes across cancer lineages are MFSD4BP1, RNA5SP164, and RNU6-919P. Each is linked with ID1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ID1-to-partner and partner-to-ID1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MFSD4BP1 grouped by ID1-low versus ID1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ID1→partner) and Y-score (partner→ID1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	MFSD4BP1 →	+0.078	+4.075	<.001	.004	3	2
BLCA	RNA5SP164 →	+0.098	+4.729	<.001	.002	3	2
BLCA	RNU6-919P →	+0.411	+2.729	<.001	.003	3	2
SKCM	GEMIN2P2 →	+0.072	+3.993	<.001	.005	3	2
SKCM	LINC02162 →	+0.108	+4.385	<.001	.008	3	2
SKCM	RPS15AP13 →	+0.268	+5.010	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 166 associations by consensus.

MFSD4BP1 by ID1 expression — SKCM

Explore this box plot interactively →